Last updated: 2025-08-11

22 Chief Of Staff jobs in San Francisco.

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Matter Intelligence

Matter Intelligence is focused on understanding all matter around us in ways that have never been possible before, utilizing advanced technologies to send data…

Chief of Staff / Business Operations Manager

San Francisco

  • Skills: business operations, strategic initiatives, cross-functional collaboration, process improvement, data analysis, stakeholder communication, scripting languages, Python, FP&A, innovative technologies
  • Level: senior
  • Type: full_time

Hive

Hive is the leading provider of cloud-based AI solutions to understand, search, and generate content, and is trusted by hundreds of the world's largest and mos…

Chief of Staff

San Francisco

  • Skills: AI solutions, cloud-based, business management, executive advising, interdepartmental collaboration, liaison, productivity, internal operations, staff management, multitasking
  • Level: mid
  • Type: full_time

Nightfall AI

Nightfall AI is the unified platform that prevents data leaks and enables secure collaboration by protecting sensitive data and controlling how it's shared. We…

Generalist Role

San Francisco

  • Skills: data security, AI-native DLP, revenue operations, strategic sales, cross-functional collaboration, stakeholder management, operational excellence, process improvement, data classification, entrepreneurship
  • Level: mid
  • Type: full_time

Altos Labs

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

Chief of Staff / Program Manager

Redwood City

  • Skills: program management, operational initiatives, business operations, budget management, senior-level advising, project leadership, cross-functional collaboration, communication skills, organizational skills, strategic initiatives
  • Level: senior
  • Type: full_time

Wonderschool

At Wonderschool, we are leveraging cutting-edge technology to solve one of the most pressing challenges facing families today: access to quality childcare. As …

Executive Assistant to the CEO

San Francisco

  • Skills: Executive Assistant, CEO Support, Strategic Efficiency, Travel Management, Communication Skills, Technology Tools, Organizational Skills, High Emotional Intelligence, Startup Environment, Childcare Innovation
  • Level: senior
  • Type: full_time

Pylon

Pylon is rewiring mortgages from the ground up. We are building the only API-first, programmatic infrastructure that fully automates credit, compliance, capita…

Founding Chief of Staff

Menlo Park

  • Skills: BizOps, mortgage, compliance, capital markets, strategic initiatives, operations, cross-functional, execution, founding team, high-growth startups
  • Level: mid
  • Type: full_time

Checkr

Checkr is building the data platform to power safe and fair decisions. Established in 2014, Checkr’s innovative technology and robust data platform help custom…

Chief of Staff

San Francisco

  • Skills: data-driven analysis, project management, stakeholder management, cross-functional collaboration, technology integration, operational excellence, strategic partner, communication liaison, process improvement, leadership
  • Level: mid
  • Type: full_time

Polly

SaaS company focusing on emerging technologies and modern tech stacks.

Chief of Staff

San Francisco

  • Skills: leadership, management consulting, program management, senior operations, SaaS, emerging technologies, tech stack, cross-functional, roadmap, hyper-growth
  • Level: mid
  • Type: full_time

Etched

Etched is building AI chips that are hard-coded for individual model architectures. Our first product (Sohu) only supports transformers, but has an order of ma…

Core Operations

Cupertino

  • Skills: AI chips, transformers, high-priority projects, strategic insights, stakeholder communication, cross-functional collaboration, operational excellence, key performance indicators, data analysis, startup environment
  • Level: mid
  • Type: full_time

Eudia

Eudia is redefining the future of legal work with AI-powered Augmented Intelligence, enabling Fortune 500 legal teams to move faster, manage risk more effectiv…

Chief of Staff - CTO

Palo Alto

  • Skills: AI-powered, Technical Program Management, Product Management, Enterprise software, Technology leadership, Executive communication, Organizational skills, Strategic insights, Innovation, Cross-functional collaboration
  • Level: mid
  • Type: full_time

Turing

Based in Palo Alto, California, Turing is one of the world's fastest-growing AI companies accelerating the advancement and deployment of powerful AI systems.

Chief of Staff (CEO's Office)

Palo Alto

  • Skills: strategic planning, executive support, board meetings, business development, organizational effectiveness, people strategy, internal communications, leadership development, decision-making, high-growth environment
  • Level: mid
  • Type: full_time

Upwork

Upwork ($UPWK) is the world’s largest work marketplace, connecting businesses with highly skilled professionals worldwide. From entrepreneurs to Fortune 100 en…

Chief of Staff to the President & CEO

Palo Alto

  • Skills: strategic thinking, executive leadership, operational detail, cross-functional collaboration, data-driven insights, stakeholder management, project management, high-pressure environments, trust-based relationships, customer-focus
  • Level: mid
  • Type: full_time

Pano AI

Pano AI is a leader in early wildfire detection and intelligence, helping fire professionals respond to fires faster and more safely—with the right equipment, …

Chief of Staff / Head of Office of CEO

San Francisco

  • Skills: wildfire detection, fire response, Gen AI, strategy, operations, project management, leadership, technical aptitude, communication skills, business acumen
  • Level: mid
  • Type: full_time

Samba TV

Samba TV tracks streaming and broadcast video across the world with our proprietary data and technology. We are on a mission to fundamentally transform the vie…

Chief Of Staff to the CEO

San Francisco

  • Skills: data-driven insights, product strategy, go-to-market strategy, cross-functional collaboration, performance analytics, user research, stakeholder management, agile methodologies, AI/ML product experience, SaaS/DaaS
  • Level: mid
  • Type: full_time

Farther

Farther is a rapidly growing RIA that combines expert advisors with cutting-edge technology - delivering a comprehensive, tailored wealth management experience…

Chief of Staff

San Francisco

  • Skills: strategic initiatives, cross-functional projects, business metrics, operations, C-level executives, process improvements, analytical skills, business growth, investment relations, wealth management
  • Level: mid
  • Type: full_time

Terradot

Our mission is to stabilize Earth’s climate by transforming nature’s most powerful permanent carbon removal process into a global climate solution. By advancin…

Chief of Staff

San Francisco

  • Skills: Chief of Staff, strategic operations, OKR cycle, board meetings, executive communication, project management, cross-functional initiatives, leadership culture, Enhanced Rock Weathering, climate technology
  • Level: mid
  • Type: full_time

TwelveLabs

TwelveLabs is pioneering the development of frontier multimodal foundation models that can see, hear and understand the world as humans do. They focus on redef…

Chief of Staff

San Francisco

  • Skills: strategic leadership, project management, operational excellence, stakeholder communication, data analysis, cross-functional collaboration, automation initiatives, product management, team productivity, business processes
  • Level: senior
  • Type: full_time

Hut 8

Hut 8 is on a mission to build and operate some of the world’s largest data centers for next-generation computing workloads, including AI, Colocation, Cloud, a…

Chief of Staff - AI

San Francisco

  • Skills: AI infrastructure, revenue operations, strategic projects, sales strategy, process improvement, operational excellence, technical content expertise, cross-functional collaboration, entrepreneurial mindset, problem-solving
  • Level: mid
  • Type: full_time

NextGen California

First 5 Alameda County is a respected organization dedicated to improving the lives of young children and their families through impactful advocacy and systems…

Chief Strategic Communications Officer

Alameda

  • Skills: strategic communications, policy advocacy, stakeholder engagement, community leadership, cross-cultural work, project management, transformative change, political influence, communications strategies, team management
  • Level: senior
  • Type: full_time

RetailReady

RetailReady is building an AI-powered supply chain compliance engine. Supply chains are still heavily reliant on paper processes and tribal knowledge, causing …

Technical Chief of Staff

San Francisco

  • Skills: compliance, supply_chain, AI, APIs, enterprise, operational_infrastructure, technical_sales, system_design, automation, customer_workflows
  • Level: mid
  • Type: full_time